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Targeting GPR120 and other fatty acid sensing GPCRs ameliorates insulin resistance and inflammatory diseases

The last decade has seen great progress in the understanding of the molecular pharmacology, physiological function and therapeutic potential of the G protein-coupled receptors. Free Fatty acids (FFAs) have been demonstrated to act as ligands of several GPCRs including GPR40, GPR43, GPR84, GPR119 and...

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Autors principals: Talukdar, Saswata, Olefsky, Jerrold M, Osborn, Olivia
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419590/
https://ncbi.nlm.nih.gov/pubmed/21663979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.04.004
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