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Targeting GPR120 and other fatty acid sensing GPCRs ameliorates insulin resistance and inflammatory diseases

The last decade has seen great progress in the understanding of the molecular pharmacology, physiological function and therapeutic potential of the G protein-coupled receptors. Free Fatty acids (FFAs) have been demonstrated to act as ligands of several GPCRs including GPR40, GPR43, GPR84, GPR119 and...

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Main Authors: Talukdar, Saswata, Olefsky, Jerrold M, Osborn, Olivia
格式: Artigo
語言:Inglês
出版: 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419590/
https://ncbi.nlm.nih.gov/pubmed/21663979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.04.004
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