A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies

The COVID-19 pandemic caused by SARS-CoV-2 has escalated into a global crisis. The spike (S) protein that mediates cell entry and membrane fusion is the current focus of vaccine and therapeutic antibody development efforts. The S protein, like many other viral fusion proteins such as HIV-1 envelope...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:bioRxiv
Autores principales: Acharya, Priyamvada, Williams, Wilton, Henderson, Rory, Janowska, Katarzyna, Manne, Kartik, Parks, Robert, Deyton, Margaret, Sprenz, Jordan, Stalls, Victoria, Kopp, Megan, Mansouri, Katayoun, Edwards, Robert J, Meyerhoff, R. Ryan, Oguin, Thomas, Sempowski, Gregory, Saunders, Kevin, Haynes, Barton F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337383/
https://ncbi.nlm.nih.gov/pubmed/32637953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.30.178897
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares