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An atomistic understanding of allosteric inhibition of glutamate racemase: a dampening of native activation dynamics

Glutamate racemases (GR) are members of the family of bacterial enzymes known as cofactor-independent racemases and epimerases and catalyze the stereoinversion of glutamate. D-amino acids are universally important for the proper construction of viable bacterial cell walls, and thus have been repeate...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Witkin, Katie R., Vance, Nicholas R., Caldwell, Colleen, Li, Quinn, Yu, Liping, Spies, M. Ashley
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337235/
https://ncbi.nlm.nih.gov/pubmed/31876113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201900642
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