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Elucidating the catalytic power of glutamate racemase by investigating a series of covalent inhibitors

The application of covalent inhibitors has experienced a renaissance within drug discovery programs in the last decade. To leverage the superior potency and drug target residence time of covalent inhibitors, there have been extensive efforts to develop highly specific covalent modifications to reduc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ChemMedChem
मुख्य लेखकों: Vance, Nicholas R., Witkin, Katie R., Rooney, Patrick W., Li, Yalan, Pope, Marshall, Spies, M. Ashley
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581216/
https://ncbi.nlm.nih.gov/pubmed/30264520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800592
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