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Elucidating the catalytic power of glutamate racemase by investigating a series of covalent inhibitors
The application of covalent inhibitors has experienced a renaissance within drug discovery programs in the last decade. To leverage the superior potency and drug target residence time of covalent inhibitors, there have been extensive efforts to develop highly specific covalent modifications to reduc...
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| Publicat a: | ChemMedChem |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581216/ https://ncbi.nlm.nih.gov/pubmed/30264520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800592 |
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