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Elucidating the catalytic power of glutamate racemase by investigating a series of covalent inhibitors

The application of covalent inhibitors has experienced a renaissance within drug discovery programs in the last decade. To leverage the superior potency and drug target residence time of covalent inhibitors, there have been extensive efforts to develop highly specific covalent modifications to reduc...

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Bibliografische gegevens
Gepubliceerd in:ChemMedChem
Hoofdauteurs: Vance, Nicholas R., Witkin, Katie R., Rooney, Patrick W., Li, Yalan, Pope, Marshall, Spies, M. Ashley
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581216/
https://ncbi.nlm.nih.gov/pubmed/30264520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800592
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