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Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9
Myeloid cells play critical and diverse roles in mammalian physiology, including tissue development and repair, innate defense against pathogens, and generation of adaptive immunity. As cells that show prolonged recruitment to sites of injury or pathology, myeloid cells represent therapeutic targets...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7336301/ https://ncbi.nlm.nih.gov/pubmed/32357367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191692 |
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