Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth

Tumour cells adapt to nutrient deprivation in vivo, yet strategies targeting the nutrient poor microenvironment remain unexplored. In melanoma, tumour cells often experience low glutamine levels, which promote cell dedifferentiation. Here, we show that dietary glutamine supplementation significantly...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ishak Gabra, Mari B., Yang, Ying, Li, Haiqing, Senapati, Parijat, Hanse, Eric A., Lowman, Xazmin H., Tran, Thai Q., Zhang, Lishi, Doan, Linda T., Xu, Xiangdong, Schones, Dustin E., Fruman, David A., Kong, Mei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335172/
https://ncbi.nlm.nih.gov/pubmed/32620791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17181-w
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