A method to quantify regional axonal transport blockade at the optic nerve head after short term intraocular pressure elevation in mice

Axonal transport blockade is an initial step in retinal ganglion cell (RGC) degeneration in glaucoma and targeting maintenance of normal axonal transport could confer neuroprotection. We present an objective, quantitative method for assessing axonal transport blockade in mouse glaucoma models. Intra...

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Vydáno v:Exp Eye Res
Hlavní autoři: Korneva, Arina, Schaub, Julie, Jefferys, Joan, Kimball, Elizabeth, Pease, Mary, Nawathe, Manasi, Johnson, Thomas V, Pitha, Ian, Quigley, Harry
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335019/
https://ncbi.nlm.nih.gov/pubmed/32353427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108035
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