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A mouse ocular explant model that enables the study of living optic nerve head events after acute and chronic intraocular pressure elevation: focusing on retinal ganglion cell axons and mitochondria

We developed an explant model of the mouse eye and optic nerve that facilitates the study of retinal ganglion cell axons and mitochondria in the living optic nerve head (ONH) in an ex vivo environment. Two transgenic mouse strains were used, one expressing yellow fluorescent protein in selected axon...

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Vydáno v:Exp Eye Res
Hlavní autoři: Kimball, Elizabeth C., Pease, Mary E., Steinhart, Matthew R., Oglesby, Ericka N., Pitha, Ian, Nguyen, Cathy, Quigley, Harry A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553309/
https://ncbi.nlm.nih.gov/pubmed/28414059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2017.04.003
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