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A method to quantify regional axonal transport blockade at the optic nerve head after short term intraocular pressure elevation in mice

Axonal transport blockade is an initial step in retinal ganglion cell (RGC) degeneration in glaucoma and targeting maintenance of normal axonal transport could confer neuroprotection. We present an objective, quantitative method for assessing axonal transport blockade in mouse glaucoma models. Intra...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Korneva, Arina, Schaub, Julie, Jefferys, Joan, Kimball, Elizabeth, Pease, Mary, Nawathe, Manasi, Johnson, Thomas V, Pitha, Ian, Quigley, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335019/
https://ncbi.nlm.nih.gov/pubmed/32353427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108035
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