Superresolution imaging reveals spatiotemporal propagation of human replication foci mediated by CTCF-organized chromatin structures

Mammalian DNA replication is initiated at numerous replication origins, which are clustered into thousands of replication domains (RDs) across the genome. However, it remains unclear whether the replication origins within each RD are activated stochastically or preferentially near certain chromatin...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Su, Qian Peter, Zhao, Ziqing Winston, Meng, Luming, Ding, Miao, Zhang, Weiwei, Li, Yongzheng, Liu, Mengzhu, Li, Rongqin, Gao, Yi-Qin, Xie, Xiaoliang Sunney, Sun, Yujie
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334649/
https://ncbi.nlm.nih.gov/pubmed/32541019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001521117
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