Superresolution imaging reveals spatiotemporal propagation of human replication foci mediated by CTCF-organized chromatin structures

Mammalian DNA replication is initiated at numerous replication origins, which are clustered into thousands of replication domains (RDs) across the genome. However, it remains unclear whether the replication origins within each RD are activated stochastically or preferentially near certain chromatin...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Su, Qian Peter, Zhao, Ziqing Winston, Meng, Luming, Ding, Miao, Zhang, Weiwei, Li, Yongzheng, Liu, Mengzhu, Li, Rongqin, Gao, Yi-Qin, Xie, Xiaoliang Sunney, Sun, Yujie
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334649/
https://ncbi.nlm.nih.gov/pubmed/32541019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001521117
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