Superresolution imaging reveals spatiotemporal propagation of human replication foci mediated by CTCF-organized chromatin structures

Mammalian DNA replication is initiated at numerous replication origins, which are clustered into thousands of replication domains (RDs) across the genome. However, it remains unclear whether the replication origins within each RD are activated stochastically or preferentially near certain chromatin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Su, Qian Peter, Zhao, Ziqing Winston, Meng, Luming, Ding, Miao, Zhang, Weiwei, Li, Yongzheng, Liu, Mengzhu, Li, Rongqin, Gao, Yi-Qin, Xie, Xiaoliang Sunney, Sun, Yujie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334649/
https://ncbi.nlm.nih.gov/pubmed/32541019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001521117
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