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Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization

DNA damage sensing proteins have been shown to localize to the sites of DNA double strand breaks (DSB) within seconds to minutes following ionizing radiation (IR) exposure, resulting in the formation of microscopically visible nuclear domains referred to as radiation-induced foci (RIF). This review...

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Detalhes bibliográficos
Main Authors: Costes, S.V., Chiolo, I., Pluth, J.M., Barcellos-Hoff, M.H., Jakob, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951968/
https://ncbi.nlm.nih.gov/pubmed/20060491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2009.12.006
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