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Independent Generation and Reactivity of 2’-Deoxyguanosin-N1-yl Radical

2’-Deoxyguanosin-N1-yl radical (dG(N(1)-H)•) is the thermodynamically favored one-electron oxidation product of 2’-deoxyguanosine (dG), the most readily oxidized native nucleoside. dG(N(1)-H)• is produced by formal dehydration of a hydroxyl radical adduct of dG, as well as by deprotonation of the co...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Zheng, Liwei, Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334105/
https://ncbi.nlm.nih.gov/pubmed/32525316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01095
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