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Independent Photochemical Generation and Reactivity of Nitrogen-Centered Purine Nucleoside Radicals From Hydrazines

Photochemical precursors that produce dA• and dG(N(2)-H)• are needed to investigate their reactivity. The synthesis of two 1,1-diphenylhydrazines (1, 2) and their use as photochemical sources of dA• and dG(N(2)-H)• is presented. Trapping studies indicate production of these radicals with good fideli...

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Bibliographische Detailangaben
Veröffentlicht in:Org Lett
Hauptverfasser: Zheng, Liwei, Lin, Lu, Qu, Ke, Adhikary, Amitava, Sevilla, Michael D., Greenberg, Marc M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711525/
https://ncbi.nlm.nih.gov/pubmed/29125775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03368
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