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Aminyl Radical Generation via Tandem Norrish Type I Photocleavage, β-Fragmentation: Independent Generation and Reactivity of the 2′-Deoxyadenosin- N6-yl Radical

Formal hydrogen atom abstraction from the nitrogen-hydrogen bonds in purine nucleosides produces reactive intermediates that are important in nucleic acid oxidation. Herein we describe an approach for the independent generation of the purine radical resulting from hydrogen atom abstraction from the...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Zheng, Liwei, Griesser, Markus, Pratt, Derek A., Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494259/
https://ncbi.nlm.nih.gov/pubmed/28318253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b00093
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