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A Synthetic and Computational Study of Tin-Free Reductive Tandem Cyclizations of Neutral Aminyl Radicals

5-exo, 5-exo Cyclizations of conformationally unbiased propargylic aminyl radicals proceed with excellent yield, chemoselectiv ity, and diastereoselectivity under tin-free reductive cyclization conditions, regardless of the electronic environments and intermediate radical stabilization resulting fro...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Sirinimal, Hansamali S., Hebert, Sebastien P., Samala, Ganesh, Chen, Heng, Rosenhauer, Gregory J., Schlegel, H. Bernhard, Stockdill, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261332/
https://ncbi.nlm.nih.gov/pubmed/30265551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02456
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