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Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network

Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in cancer genomes occur due to internal and external mutagenesis forces. Decoding the mutational processes by examining their unique patterns has successfully revealed many known and novel signatures from...

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Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Pei, Guangsheng, Hu, Ruifeng, Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334101/
https://ncbi.nlm.nih.gov/pubmed/32528130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1343-z
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