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Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network

Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in cancer genomes occur due to internal and external mutagenesis forces. Decoding the mutational processes by examining their unique patterns has successfully revealed many known and novel signatures from...

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Publicat a:Oncogene
Autors principals: Pei, Guangsheng, Hu, Ruifeng, Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334101/
https://ncbi.nlm.nih.gov/pubmed/32528130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1343-z
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