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Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network

Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in cancer genomes occur due to internal and external mutagenesis forces. Decoding the mutational processes by examining their unique patterns has successfully revealed many known and novel signatures from...

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Bibliographic Details
Published in:Oncogene
Main Authors: Pei, Guangsheng, Hu, Ruifeng, Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7334101/
https://ncbi.nlm.nih.gov/pubmed/32528130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1343-z
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