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Deep generative neural network for accurate drug response imputation

Drug response differs substantially in cancer patients due to inter- and intra-tumor heterogeneity. Particularly, transcriptome context, especially tumor microenvironment, has been shown playing a significant role in shaping the actual treatment outcome. In this study, we develop a deep variational...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Jia, Peilin, Hu, Ruifeng, Pei, Guangsheng, Dai, Yulin, Wang, Yin-Ying, Zhao, Zhongming
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979803/
https://ncbi.nlm.nih.gov/pubmed/33741950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21997-5
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