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Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders

As the most complex organ of the human body, the brain is composed of diverse regions, each consisting of distinct cell types and their respective cellular interactions. Human brain development involves a finely tuned cascade of interactive events. These include spatiotemporal gene expression change...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Res
Main Authors: Pei, Guangsheng, Wang, Yin-Ying, Simon, Lukas M., Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849392/
https://ncbi.nlm.nih.gov/pubmed/33272935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265769.120
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