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Gene expression imputation and cell-type deconvolution in human brain with spatiotemporal precision and its implications for brain-related disorders

As the most complex organ of the human body, the brain is composed of diverse regions, each consisting of distinct cell types and their respective cellular interactions. Human brain development involves a finely tuned cascade of interactive events. These include spatiotemporal gene expression change...

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Foilsithe in:Genome Res
Main Authors: Pei, Guangsheng, Wang, Yin-Ying, Simon, Lukas M., Dai, Yulin, Zhao, Zhongming, Jia, Peilin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849392/
https://ncbi.nlm.nih.gov/pubmed/33272935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.265769.120
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