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Improved targeting of an anti‐TAG‐72 antibody drug conjugate for the treatment of ovarian cancer

INTRODUCTION: Ovarian cancer has only a 17% 5‐year survival rate in patients diagnosed with late stage disease. Tumor‐associated glycoprotein‐72 (TAG72), expressed in 88% of all stages of ovarian cancer, is an excellent candidate for antibody‐targeted therapy, as it is not expressed in normal human...

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Bibliografiske detaljer
Udgivet i:Cancer Med
Main Authors: Minnix, Megan, Li, Lin, Yazaki, Paul, Chea, Junie, Poku, Erasmus, Colcher, David, Shively, John E.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333846/
https://ncbi.nlm.nih.gov/pubmed/32368864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3078
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