A Gq Biased Small Molecule Active at the TSH Receptor

G protein coupled receptors (GPCRs) can lead to G protein and non-G protein initiated signals. By virtue of its structural property, the TSH receptor (TSHR) has a unique ability to engage different G proteins making it highly amenable to selective signaling. In this study, we describe the identifica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Endocrinol (Lausanne)
Prif Awduron: Latif, Rauf, Morshed, Syed A., Ma, Risheng, Tokat, Bengu, Mezei, Mihaly, Davies, Terry F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Endocrinology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333667/
https://ncbi.nlm.nih.gov/pubmed/32676053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00372
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