New Small Molecule Agonists to the Thyrotropin Receptor

BACKGROUND: Novel small molecular ligands (SMLs) to the thyrotropin receptor (TSHR) have potential as improved molecular probes and as therapeutic agents for the treatment of thyroid dysfunction and thyroid cancer. METHODS: To identify novel SMLs to the TSHR, we developed a transcription-based lucif...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Latif, Rauf, Ali, M. Rejwan, Ma, Risheng, David, Martine, Morshed, Syed A., Ohlmeyer, Michael, Felsenfeld, Dan P., Lau, Zerlina, Mezei, Mihaly, Davies, Terry F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original StudiesThyroid Dysfunction: Hypothyroidism, Thyrotoxicosis, and Thyroid Function Tests
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291085/
https://ncbi.nlm.nih.gov/pubmed/25333622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2014.0119
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