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Cleavage Region Thyrotropin Receptor Antibodies Influence Thyroid Cell Survival In Vivo

Background: Graves' disease is associated with thyrotropin receptor (TSHR) antibodies of variable bioactivity. Recently, antibodies have been characterized that bind to the cleavage region of the TSHR ectodomain (C-TSHR-Ab), and their ability to induce thyroid cell apoptosis in vitro via excess...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Morshed, Syed A., Ma, Risheng, Latif, Rauf, Davies, Terry F.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648196/
https://ncbi.nlm.nih.gov/pubmed/31025602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2018.0633
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