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Long Term Rescue of the TSH Receptor Knock-Out Mouse – Thyroid Stem Cell Transplantation Restores Thyroid Function

The synergistic activation of transcription factors can lead to thyroid progenitor cell speciation. We have previously shown in vitro that mouse or human stem cells, expressing the transcription factors NKx2-1 and Pax8, can differentiate into thyroid neo-follicular structures (TFS). We now show that...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Latif, Rauf, Ma, Risheng, Morshed, Syed A., Tokat, Bengu, Davies, Terry F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283971/
https://ncbi.nlm.nih.gov/pubmed/34276566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.706101
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