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MALT1 targeting suppresses CARD14‐induced psoriatic dermatitis in mice
CARD14 gain‐of‐function mutations cause psoriasis in humans and mice. Together with BCL10 and the protease MALT1, mutant CARD14 forms a signaling node that mediates increased NF‐κB signaling and proinflammatory gene expression in keratinocytes. However, it remains unclear whether psoriasis in respon...
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| 出版年: | EMBO Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7332803/ https://ncbi.nlm.nih.gov/pubmed/32343482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949237 |
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