Overexpression of HGF/MET axis along with p53 inhibition induces de novo glioma formation in mice

BACKGROUND: Aberrant MET receptor tyrosine kinase (RTK) activation leads to invasive tumor growth in different types of cancer. Overexpression of MET and its ligand hepatocyte growth factor (HGF) occurs more frequently in glioblastoma (GBM) than in low-grade gliomas. Although we have shown previousl...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Neurooncol Adv
Autori principali: Qin, Yuan, Musket, Anna, Kou, Jianqun, Preiszner, Johanna, Tschida, Barbara R, Qin, Anna, Land, Craig A, Staal, Ben, Kang, Liang, Tanner, Kirk, Jiang, Yong, Schweitzer, John B, Largaespada, David A, Xie, Qian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332240/
https://ncbi.nlm.nih.gov/pubmed/32642717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa067
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