TMOD-44. HGF-AUTOCRINE ACTIVATION OF MET RECEPTOR TYROSINE KINASE INDUCES DE NOVO GLIOMA FORMATION IN MICE

Genomic profiling of glioblastoma (GBM) has identified 4 molecular classifications, with the mesenchymal subtype as the most invasive phenotype resulting in short survival. The Met oncogene activation leads to invasive tumor growth and is a mesenchymal marker. Within the same GBMs, elevated MET acti...

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Publicado no:Neuro Oncol
Main Authors: Kou, Jianqun, Preiszner, Johanna, Johnson, Jennifer, Tschida, Barbara, Staal, Benjamin, Kang, Liang, Tanner, Kirk, Schweitzer, John, Largaespada, David, Xie, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692771/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1080
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