Balance Between Rapid Delayed Rectifier K(+) Current and Late Na(+) Current on Ventricular Repolarization: An Effective Antiarrhythmic Target?

BACKGROUND: Rapid delayed rectifier K(+) current (I(Kr)) and late Na(+) current (I(NaL)) significantly shape the cardiac action potential (AP). Changes in their magnitudes can cause either long or short QT syndromes (LQT, SQT) associated with malignant ventricular arrhythmias and sudden cardiac deat...

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書誌詳細
出版年:Circ Arrhythm Electrophysiol
主要な著者: Hegyi, Bence, Chen-Izu, Ye, Izu, Leighton T., Rajamani, Sridharan, Belardinelli, Luiz, Bers, Donald M., Bányász, Tamás
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331791/
https://ncbi.nlm.nih.gov/pubmed/32202931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.119.008130
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