Induced Pluripotent Stem Cells Derived From Two Idiopathic Azoospermia Patients Display Compromised Differentiation Potential for Primordial Germ Cell Fate

At present, the etiology of most non-obstructive azoospermia (NOA) remains unclear. In vitro generation of patient-specific induced pluripotent stem cells (iPSCs) is an effective approach for exploring the mechanisms of human disease. Here, we established iPSCs from two patients with idiopathic NOA...

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Detalles Bibliográficos
Publicado en:Front Cell Dev Biol
Main Authors: Fang, Fang, Li, Zili, Zhao, Qian, Ye, Zhen, Gu, Xiuli, Pan, Feng, Li, Honggang, Xiang, Wenpei, Xiong, Chengliang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7331483/
https://ncbi.nlm.nih.gov/pubmed/32671061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00432
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