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Analysis of multi-lineage gene expression dynamics during primordial germ cell induction from human induced pluripotent stem cells
BACKGROUND: In mammals, specification of primordial germ cells (PGCs) is established in the early postimplantation embryo. The bone morphogenetic protein (BMP)-SMAD and WNT3-β-catenin signaling initiate the gene regulatory network for PGC specification. The activation of SOX17-BLIMP1 axis is critic...
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| Publicado no: | Stem Cell Res Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7055065/ https://ncbi.nlm.nih.gov/pubmed/32127035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01620-y |
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