NLRP3 inflammasome via IL-1β regulates PCSK9 secretion

Background: Both PCSK9 and NLRP3 inflammasome play important roles in atherogenesis. This study was designed to test the hypothesis that NLRP3 inflammasome via IL-1β induces PCSK9 secretion. The inter-twined relationship between NLRP3 inflammasome, IL-1β and PCSK9 may be relevant in atherogenesis. M...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Ding, Zufeng, Wang, Xianwei, Liu, Shijie, Zhou, Sichang, Kore, Rajshekhar A, Mu, Shengyu, Deng, Xiaoyan, Fan, Yubo, Mehta, Jawahar L
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330863/
https://ncbi.nlm.nih.gov/pubmed/32641981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45939
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