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Concentration polarization of ox-LDL activates autophagy and apoptosis via regulating LOX-1expression
Here we demonstrate that “concentration polarization” of ox-LDL enhances LOX-1 expression and ox-LDL uptake. It damages cell surface heparan sulfate proteoglycans (HSPG) and activates LOX-1 dependent autophagy and apoptosis. We also show that ox-LDL concentration polarization occurs on the surface o...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6752645/ https://ncbi.nlm.nih.gov/pubmed/23807658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02091 |
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