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Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities
APOE is a well-studied gene with multiple effects on aging and longevity. The gene has three alleles: e2, e3, and e4, whose frequencies vary by ethnicity. While the e2 is associated with healthy cognitive aging, the e4 allele is associated with Alzheimer’s disease and early mortality and therefore i...
Shranjeno v:
| izdano v: | J Gerontol A Biol Sci Med Sci |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7330482/ https://ncbi.nlm.nih.gov/pubmed/31724059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz179 |
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