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Varying Effects of APOE Alleles on Extreme Longevity in European Ethnicities
APOE is a well-studied gene with multiple effects on aging and longevity. The gene has three alleles: e2, e3, and e4, whose frequencies vary by ethnicity. While the e2 is associated with healthy cognitive aging, the e4 allele is associated with Alzheimer’s disease and early mortality and therefore i...
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| Publicat a: | J Gerontol A Biol Sci Med Sci |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7330482/ https://ncbi.nlm.nih.gov/pubmed/31724059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glz179 |
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