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Effects of FOXO3 Polymorphisms on Survival to Extreme Longevity in Four Centenarian Studies

Previous studies note specific FOXO3 single-nucleotide polymorphisms (SNPs) associated with human longevity. However, it is not clear if these SNPs influence mortality risk beyond the oldest 1 percentile of survival. Using data from four longevity studies (total n = 8,266, age range 96–119 years for...

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Bibliografiske detaljer
Udgivet i:J Gerontol A Biol Sci Med Sci
Main Authors: Bae, Harold, Gurinovich, Anastasia, Malovini, Alberto, Atzmon, Gil, Andersen, Stacy L, Villa, Francesco, Barzilai, Nir, Puca, Annibale, Perls, Thomas T, Sebastiani, Paola
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175020/
https://ncbi.nlm.nih.gov/pubmed/28977569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glx124
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