ETHNIC-SPECIFIC EFFECT OF APOE ALLELES ON EXTREME LONGEVITY

Apolipoprotein E (APOE) is a well-studied gene with multiple effects on aging and longevity. The gene has 3 alleles: e2, e3 and e4 whose frequencies vary by ethnicity, and e4 is a known risk factor for Alzheimer’s, while e2 is associated with healthy aging and longevity. We analyzed ethnic specific...

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Udgivet i:Innov Aging
Main Authors: Gurinovich, A, Bae, H, Andersen, S, Puca, A, Atzmon, G, Barzilai, N, Perls, T, Sebastiani, P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Abstracts
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6229862/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.373
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