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Genome-wide investigation of gene-cancer associations for the prediction of novel therapeutic targets in oncology

A major cause of failed drug discovery programs is suboptimal target selection, resulting in the development of drug candidates that are potent inhibitors, but ineffective at treating the disease. In the genomics era, the availability of large biomedical datasets with genome-wide readouts has the po...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Bazaga, Adrián, Leggate, Dan, Weisser, Hendrik
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330039/
https://ncbi.nlm.nih.gov/pubmed/32612205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67846-1
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