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Genome-wide investigation of gene-cancer associations for the prediction of novel therapeutic targets in oncology

A major cause of failed drug discovery programs is suboptimal target selection, resulting in the development of drug candidates that are potent inhibitors, but ineffective at treating the disease. In the genomics era, the availability of large biomedical datasets with genome-wide readouts has the po...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bazaga, Adrián, Leggate, Dan, Weisser, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330039/
https://ncbi.nlm.nih.gov/pubmed/32612205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67846-1
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