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In silico prediction of novel therapeutic targets using gene–disease association data

BACKGROUND: Target identification and validation is a pressing challenge in the pharmaceutical industry, with many of the programmes that fail for efficacy reasons showing poor association between the drug target and the disease. Computational prediction of successful targets could have a considerab...

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Библиографические подробности
Опубликовано в: :J Transl Med
Главные авторы: Ferrero, Enrico, Dunham, Ian, Sanseau, Philippe
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576250/
https://ncbi.nlm.nih.gov/pubmed/28851378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1285-6
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