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In silico prediction of novel therapeutic targets using gene–disease association data

BACKGROUND: Target identification and validation is a pressing challenge in the pharmaceutical industry, with many of the programmes that fail for efficacy reasons showing poor association between the drug target and the disease. Computational prediction of successful targets could have a considerab...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Transl Med
Päätekijät: Ferrero, Enrico, Dunham, Ian, Sanseau, Philippe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576250/
https://ncbi.nlm.nih.gov/pubmed/28851378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1285-6
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