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In silico prediction of novel therapeutic targets using gene–disease association data

BACKGROUND: Target identification and validation is a pressing challenge in the pharmaceutical industry, with many of the programmes that fail for efficacy reasons showing poor association between the drug target and the disease. Computational prediction of successful targets could have a considerab...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ferrero, Enrico, Dunham, Ian, Sanseau, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576250/
https://ncbi.nlm.nih.gov/pubmed/28851378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1285-6
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