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High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer's disease

Alzheimer's disease (AD), the most common cause of dementia, affects millions of people worldwide. Suggested mechanisms of neurotoxicity in AD include impaired calcium (Ca(2+)) homeostasis and mitochondrial dysfunction, both contributing to neuronal damage. Little was known about the exact mito...

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Vydáno v:Cell Stress
Hlavní autoři: Calvo-Rodriguez, Maria, Bacskai, Brian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Shared Science Publishers OG 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328672/
https://ncbi.nlm.nih.gov/pubmed/32656500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2020.07.226
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