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High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer's disease

Alzheimer's disease (AD), the most common cause of dementia, affects millions of people worldwide. Suggested mechanisms of neurotoxicity in AD include impaired calcium (Ca(2+)) homeostasis and mitochondrial dysfunction, both contributing to neuronal damage. Little was known about the exact mito...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Stress
Hauptverfasser: Calvo-Rodriguez, Maria, Bacskai, Brian J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shared Science Publishers OG 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328672/
https://ncbi.nlm.nih.gov/pubmed/32656500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2020.07.226
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