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High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer's disease

Alzheimer's disease (AD), the most common cause of dementia, affects millions of people worldwide. Suggested mechanisms of neurotoxicity in AD include impaired calcium (Ca(2+)) homeostasis and mitochondrial dysfunction, both contributing to neuronal damage. Little was known about the exact mito...

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Detalhes bibliográficos
Publicado no:Cell Stress
Main Authors: Calvo-Rodriguez, Maria, Bacskai, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7328672/
https://ncbi.nlm.nih.gov/pubmed/32656500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2020.07.226
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