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TIM3 comes of age as an inhibitory receptor
T cell immunoglobulin and mucin domain-containing protein 3 (TIM3), a member of the TIM family, was originally identified as a receptor expressed on interferon-γ-producing CD4(+) and CD8(+) T cells. Initial data indicated that TIM3 functioned as a ‘co-inhibitory’ or ‘checkpoint’ receptor, but due to...
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| Publicat a: | Nat Rev Immunol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7327798/ https://ncbi.nlm.nih.gov/pubmed/31676858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-019-0224-6 |
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