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Emerging Tim-3 functions in anti-microbial and tumor immunity
T cell immunoglobulin-3 (Tim-3) was identified as a marker of differentiated IFN-γ-producing CD4(+) T helper type 1 and CD8(+) T cytotoxic type 1 cells. The interaction of Tim-3 with its ligand, galectin-9 (Gal-9), induces cell death and in vivo blockade of this interaction results in exacerbated au...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164311/ https://ncbi.nlm.nih.gov/pubmed/21697013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2011.05.003 |
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