Transforming activities of the NUP98-KMT2A fusion gene associated with myelodysplasia and acute myeloid leukemia

Inv(11)(p15q23), found in myelodysplastic syndromes and acute myeloid leukemia, leads to expression of a fusion protein consisting of the N-terminal of nucleoporin 98 (NUP98) and the majority of the lysine methyltransferase 2A (KMT2A). To explore the transforming potential of this fusion we establis...

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Publicado no:Haematologica
Main Authors: Fisher, James N., Thanasopoulou, Angeliki, Juge, Sabine, Tzankov, Alexandar, Bagger, Frederik O., Mendez, Max A., Peters, Antoine H.F.M., Schwaller, Juerg
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7327646/
https://ncbi.nlm.nih.gov/pubmed/31558671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.219188
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