A Novel Inducible Mouse Model of MLL-ENL-driven Mixed-lineage Acute Leukemia

Previous retroviral and knock-in approaches to model human t(11;19)(+) acute mixed-lineage leukemia in mice resulted in myeloproliferation and acute myeloid leukemia not fully recapitulating the human disease. The authors established a doxycycline (DOX)-inducible transgenic mouse model “iMLL-ENL” in...

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Publicado no:Hemasphere
Main Authors: Stavropoulou, Vaia, Almosailleakh, Marwa, Royo, Hélène, Spetz, Jean-François, Juge, Sabine, Brault, Laurent, Kopp, Patrick, Iacovino, Michelina, Kyba, Michael, Tzankov, Alexandar, Stadler, Michael B., Cazzaniga, Gianni, Peters, Antoine H.F.M., Schwaller, Juerg
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745998/
https://ncbi.nlm.nih.gov/pubmed/31723780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000051
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